I’ve generally only driven the stretches between Memphis and Albuquerque, and Memphis to Knoxville. Places I’ve almost always overnighted are El Reno, OK, Amarillo, TX, Shamrock, TX, or Tucumcari, NM. Never had any issues in any of them. Amarillo has pretty good places to eat, and the iconic Big Texan Steakhouse - which I wasn’t overly impressed with, but it is famous. Not much to look at between the Ozarks and Cline’s Corner, and like Bravo says, get gas before you need it out west.