I'm a fan of "combo" set irons, but maybe not to quite the extent you're looking at. Currently I have 5, 6, & 7 irons are Cally Apex CF16 while the 8, 9 and P are Apex Pro. The lofts on the longer irons are weakened a bit to more closely match the Pros. I've generally hit 8-P really well and then the ball striking starts falling off and can be pretty poor with a 5i for me so I'm looking for forgiveness. In the past when I played better the 6-P would be a "Pro" type model, but really I just don't like a really large SGI iron and a lot of offset until I get to a 5 iron.....and for awhile I stopped carrying a 5 iron and carried a 5 hybrid.
Any way I agree with your concept of having your clubs be built for the shots you want to hit. You just may want to make sure you can cover your yardage gaps. That can get tricky with different heads and shafts. I tried a set once with heavier PX shafts in the 8-P and lighter PX HL in the 5-7 (the 6-P were XHot Pro and the 5i was just XHot) and the results were mixed at best. I think I was on the right track, but never got the shaft profiles quite right among other variables.
I had similar discussions with the fitter than built my Cally set. He was okay with even having a club in the bag that you only use for the tee shot on 1 or 2 holes, but warned me about getting too caught up in trying to make a club for too specific a shot that you may rarely hit. I have always wanted every club in my bag to be a favorite, but that rarely works at my skill (or lack of) level. If I was retired maybe I would experiment more again, but it felt like I was just heading down this rabbit hole and making things too complex.