Hard to win on the road. But... I think 3 teams this week will pick up road wins (possibly 4) this week.
I think the Saints will surprise Seattle despite the absence of Brees, and despite Bridgewater getting his first start since 2015. I won't be surprised, however, if NO wins. Seattle eked out the season opener against Cincy by a single point, and barely scraped by Pittsburgh (2 pts) despite a disheveled Steelers team with little talent and the absence of Big Ben for the second half of the game.
Rams @ Browns - Mayfield is a loose cannon. 4 picks in two games, and a feeling that the fresh paint is already starting to fade in Cleveland. Still better than they used to be, but still Cleveland.
Chicago @ Washington - Chicago.
On the Fence:
Lions @ Eagles - At this rate, the Birds will be placing employment ads in the Philadelphia Inquirer long before week 8. As much as I want to favor the home team, especially against the Lions, I'm not getting the warm fuzzies about this one.